Measure Journal Volume 10 Article 18

Optimizing Data Logger Setup and Use for Refrigerated Vaccine Temperature Monitoring

NCSLI Measure | Vol. 10 No. 3 (2015) | https://doi.org/10.1080/19315775.2015.11721733
Publisher NCSL International | Published September 2015 | pp. 28-37

Abstract Authors References Article PDF Citation(s)

Abstract

Accidental freezing of refrigerated vaccine represents a significant public and private healthcare cost. Freeze-damaged vaccines lose their effectiveness, putting public health at risk. U.S. immunization programs have strengthened vaccine storage and handling recommendations to mitigate this danger. However, current publications describing the setup and configuration of vaccine temperature monitoring devices allow for a range of untested interpretations. In this paper, we report on our study of specific temperature monitoring setup variables, including vial size, thermal buffer type, buffer fluid concentration, and placement of the probe-in-vial setup, in an effort to provide definitive guidance on the selection of an optimal temperature monitoring setup and methodology for use in vaccine storage refrigerators.

(Print: ISSN 1931-5775) (Online: ISSN 2381-0580)
©2015 NCSL International

Authors

Michal J. Chojnacky 0000-0002-7872-6413

National Institute of Standards and Technology
Sensor Science Division
Thermodynamic Metrology
Gaithersburg, MD

L.F. Chaves Santacruz

National Institute of Standards and Technology
Sensor Science Division
Thermodynamic Metrology
Gaithersburg, MD

Laboratorio Costarricense de Metrologia
Depatamento de Metrologia Fisica Laboratorio de Temperatura
San Jose, Costa Rica

W. Wyatt Miller

National Institute of Standards and Technology
Sensor Science Division
Thermodynamic Metrology
Gaithersburg, MD

Gregory F. Strouse

National Institute of Standards and Technology
Sensor Science Division
Thermodynamic Metrology
Gaithersburg, MD

References

[1] M. Chojnacky, W. Miller, D. Ripple, and G. Strouse, "Thermal Analysis of Refrigeration Systems Used for Vaccine Storage," NIST Interagency or Internal Report (NISTIR) 7656, 2009.

https://doi.org/10.6028/NIST.IR.7656

[2] M. Chojnacky, W. Miller, and G. Strouse, "Thermal Analysis of Refrigeration Systems Used for Vaccine Storage: Report on Pharmaceutical Grade Refrigerator and Household Refrigerator/Freezer," NIST Interagency or Internal Report (NISTIR) 7753, 2010.

https://doi.org/10.6028/NIST.IR.7753

[3] M. Chojnacky, W. Miller, and G. Strouse, "Data Logger Thermometers for Vaccine Temperature Monitoring," NIST Interagency or Internal Report (NISTIR) 7899, 2012.

https://doi.org/10.6028/NIST.IR.7899

[4] M. Chojnacky, W. Miller, and G. Strouse, "Thermal Analysis of a Small Pharmaceutical Refrigerator for Vaccine Storage," NIST Interagency or Internal Report (NISTIR) 7900, 2012.

https://doi.org/10.6028/NIST.IR.7900

[5] M. Chojnacky, W. Miller, and G. Strouse, "Methods for accurate cold-chain temperature monitoring using digital data-logger thermometers," AIP Conference Proceedings, vol. 1552, pp. 1014-1019, 2013.

https://doi.org/10.1063/1.4819683

[6] Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, "Vaccine Storage and Handling Toolkit," May 2014 http://www.cdc.gov/vaccines/recs/storage/toolkit/storage-handling-toolkit.pdf

[7] ESDU, "Thermal conductivity of liquids: Mixtures," ESDU 88004, Amendment (A), September 2005.

[8] ESDU, "Thermal conductivity of liquids: Glycols, glycerol and their aqueous solutions," ESDU 99013, Amendment (B), September 2005.

[9] B. Mangum, "Reproducibility of the Temperature of the Ice Point in Routine Measurements," NIST Technical Note 1411, 1995.

https://doi.org/10.6028/NIST.TN.1411

[10] ILAC/OIML, "Guidelines for the determination of calibration intervals of measuring instruments," ILAC G24 / OIML D10, 2007.

[11] D. Matthias, J. Robertson, M. Garrison, S. Newland, and C. Nelson, "Freezing temperatures in the vaccine cold chain: A systematic literature review," Vaccine, vol. 25, pp. 3980-3986, 2007.

https://doi.org/10.1016/j.vaccine.2007.02.052

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Citation(s)

M. Chojnacky, "Optimizing Data Logger Setup and Use for Refrigerated Vaccine Temperature Monitoring," NCSLI Measure, Vol. 10 No. 3, pp. 28-37, https://doi.org/10.1080/19315775.2015.11721733

Issue

Vol. 10 No. 1 (2015)
Vol. 10 No. 2 (2015)
Vol. 10 No. 3 (2015)
Vol. 10 No. 4 (2015)